Types of Glaucoma: Causes, Symptoms, and Treatments

Glaucoma, often called the "silent thief of sight," is a group of eye conditions that cause damage to the optic nerve. This damage is typically the result of elevated pressure within the eye (intraocular pressure) and, if left untreated, can lead to permanent vision loss.

What is Glaucoma?

Glaucoma is not a single disease but a group of eye disorders that share a common characteristic: damage to the optic nerve. The optic nerve plays a crucial role in transferring visual information from your eye to your brain. When this nerve becomes damaged, it can lead to blind spots in your vision or, in severe cases, complete blindness.

The condition often develops gradually without presenting symptoms in its early stages, making regular eye exams essential. While elevated intraocular pressure is a major risk factor, glaucoma can also occur in people with normal eye pressure (known as normal-tension glaucoma).

Types of Glaucoma

1. Primary Open-Angle Glaucoma (POAG)

Causes

Primary open-angle glaucoma is the most common type of glaucoma. It occurs when the eye's drainage system, known as the trabecular meshwork, becomes partially blocked. This results in a slow build-up of intraocular pressure, which gradually damages the optic nerve. Risk factors include age, family history, higher intraocular pressure, and being of African or Hispanic descent.

Symptoms

POAG develops slowly and is usually asymptomatic in its early stages. Over time, individuals may notice blind spots in their peripheral vision, which can progress to tunnel vision if untreated.

Treatment

POAG is often managed with medications, such as prescription eye drops that lower eye pressure by reducing fluid production or increasing drainage. Additional options include laser therapy (like selective laser trabeculoplasty) or surgery to aid fluid drainage.

2. Angle-Closure Glaucoma

Causes

Angle-closure glaucoma, also known as closed-angle glaucoma, occurs when the drainage angle between the iris and cornea becomes physically blocked. This prevents fluid from exiting the eye, leading to a sudden increase in intraocular pressure. While this condition can develop slowly (chronic angle-closure glaucoma), it often presents as an acute attack.

Symptoms

Acute angle-closure glaucoma is a medical emergency. Symptoms include severe eye pain, headache, nausea, blurred vision, and seeing halos around lights. Chronic cases may develop more gradually with mild vision changes.

Treatment

Acute angle-closure glaucoma requires immediate medical attention. Treatment often includes medications to quickly lower eye pressure and laser or surgical procedures, such as peripheral iridotomy, to create a new drainage pathway.

3. Normal-Tension Glaucoma (NTG)

Causes

Normal-tension glaucoma is a form of open-angle glaucoma where optic nerve damage occurs despite normal intraocular pressure levels. The exact cause is not fully understood, but it is believed that poor blood flow to the optic nerve or increased sensitivity of the nerve may play a role. Risk factors include a family history of glaucoma, low blood pressure, and conditions like migraines.

Symptoms

Similar to POAG, NTG progresses slowly and may result in peripheral vision loss. Blind spots may become noticeable over time.

Treatment

Treatment for NTG focuses on reducing intraocular pressure even further. This may involve the use of eye drops, laser therapy, or surgery. Additionally, measures to optimise blood flow to the optic nerve, such as managing systemic health, may be recommended.

4. Congenital Glaucoma

Causes

Congenital glaucoma is a rare condition that occurs in infants and young children due to developmental abnormalities in the eye's drainage system. It is usually an inherited condition caused by genetic mutations.

Symptoms

Signs of congenital glaucoma include unusually large eyes, sensitivity to light, excessive tearing, and cloudy corneas. Parents may notice these signs early in their child's development.

Treatment

Congenital glaucoma often requires surgical intervention to correct drainage and reduce intraocular pressure. Early diagnosis and treatment are crucial to preserving the child’s vision.

5. Secondary Glaucoma

Causes

Secondary glaucoma arises as a result of another medical condition, trauma, or medication. Conditions such as uveitis (eye inflammation), diabetes, or prolonged steroid use can contribute to its development. Eye injuries and surgeries can also increase the risk.

Symptoms

Symptoms vary depending on the underlying cause but may include redness, pain, blurred vision, and increased intraocular pressure.

Treatment

Treating secondary glaucoma involves addressing the underlying condition while also managing intraocular pressure with medications, laser therapy, or surgery.

Risk Factors for Glaucoma

Glaucoma can affect anyone, but certain factors increase the risk, including:

  • Age (60 and older, or 40 and older for African, Asian, or Hispanic populations)
  • Family history of glaucoma
  • Elevated intraocular pressure
  • Thin corneas
  • Medical conditions such as diabetes or hypertension
  • Long-term corticosteroid use
  • Previous eye injury

Steps to Protect Your Vision

While glaucoma cannot always be prevented, early detection and intervention can significantly reduce the risk of vision loss. Here's how you can protect your eye health:

  • Regular Eye Exams: Schedule comprehensive eye exams to check for optic nerve health and intraocular pressure, especially if you're in a high-risk group.
  • Lifestyle Choices: Maintain a healthy lifestyle that includes regular exercise, a balanced diet, and managing systemic health issues like diabetes and hypertension.
  • Protect Your Eyes: Wear protective eyewear to prevent injuries and reduce the risk of secondary glaucoma.
  • Adherence to Treatment Plans: If diagnosed, follow your treatment plan diligently to manage intraocular pressure and prevent further damage.

Conclusion

Glaucoma is a leading cause of irreversible vision loss, but it doesn't have to be. By understanding the different types of glaucoma, recognising their symptoms, and seeking early treatment, you can take charge of your eye health.